Understanding Your Serotonin

January 20, 2020

Written by

Lucas Aoun

Founder @ Ergogenic Health


👉🏽 HOW WELL DO YOU KNOW SEROTONIN?⁣
In this post I will explore a very important receptor found in the brain that serotonin can bind to. The 5-HT1A (Serotonin) receptor. ⁣


😇WHAT MAKES THIS RECEPTOR SPECIAL?⁣
The 5-HT1A receptor is 1 of the 14 serotonin receptor sub-types found in the brain. ⁣
Many pharmaceutical antidepressants, herbs, nootropics and exotic compounds are known to interact with this receptor. It influences the way ⁣
you experience life in a very significant way. ⁣

⚠️WHAT HAPPENS WITH OVERACTIVATION/DESENSITISATION: ⁣
▷ANTICIPATORY ANXIETY; e.g "can't wait for" behavior, impatient in lines, awaiting the arrival of goods causing anxiety, ⁣
or anxiously awaiting paycheck. ⁣
▷Dampened Emotions; bluntness, shallow faced, expressionless, indifferent. ⁣
This is because of serotonin 5-HT1A’s interactions with the opioidergic systems, as well inhibition of ⁣
amygdala dopamine and glutamate activity which normally act to facilitate these emotions.⁣
▷Low / Slow Sexual response, low libido, delayed ejaculation, erectile dysfunction, hypoactive sexual desire/arousal in women.⁣
(References available on request)⁣


💡WHAT ALTERS TO THIS RECEPTOR?⁣
-Acetyl L-Carnitine⁣
-Ashwagandha⁣
-Cinnamon⁣
-Creatine⁣
-Zinc⁣
-Berberine⁣
-St John’s Wort⁣
-Zeolite⁣
-SSRI’s⁣
-Yohimbine⁣
-Ginkgo Biloba⁣
(References available on request)⁣

💥TAKEAWAY:⁣
There are many people living with dysfunctional 5-HT1A receptor sensitivity and activity. Be cautious using compounds that significantly interact with this receptor since it really acts as the GATEKEEPER to modulate BRAIN-WIDE serotonin activity.⁣